ribosome$70639$ - определение. Что такое ribosome$70639$
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Что (кто) такое ribosome$70639$ - определение

A CELLULAR PROCESS THAT RESULTS IN THE BIOSYNTHESIS OF CONSTITUENT MACROMOLECULES, ASSEMBLY, AND ARRANGEMENT OF CONSTITUENT PARTS OF RIBOSOME SUBUNITS; INCLUDES TRANSPORT TO THE SITES OF PROTEIN SYNTHESIS
Ribosome synthesis; Ribosome Biogenesis
  • rRNA biogenesis and assembly in prokaryote and eukaryotes. Notably in Eukaryotes 5S rRNA is synthesised by [[RNA polymerase III]] whereas other eukaryote rRNA molecules are transcribed by [[RNA polymerase I]].

Ribosome biogenesis         
Ribosome biogenesis is the process of making ribosomes. In prokaryotes, this process takes place in the cytoplasm with the transcription of many ribosome gene operons.
Ribosome recycling factor         
MAMMALIAN PROTEIN FOUND IN HOMO SAPIENS
Ribosome Recycling Factor; Ribosome release factor
Ribosome recycling factor or ribosome release factor (RRF) is a protein found in bacterial cells as well as eukaryotic organelles, specifically mitochondria and chloroplasts. It functions to recycle ribosomes after completion of protein synthesis (bacterial translation).
Ribosome profiling         
  • Ribosome Profiling in brief
TECHNIQUE USED TO DETERMINE WHICH MRNAS ARE BEING ACTIVELY TRANSLATED
Ribo-Seq; Ribosomal profiling; Ribosome footprinting
Ribosome profiling, or Ribo-Seq (also named ribosome footprinting), is an adaptation of a technique developed by Joan Steitz and Marilyn Kozak almost 50 years ago that Nicholas Ingolia and Jonathan Weissman adapted to work with next generation sequencing that uses specialized messenger RNA (mRNA) sequencing to determine which mRNAs are being actively translated. A related technique that can also be used to determine which mRNAs are being actively translated is the Translating Ribosome Affinity Purification (TRAP) methodology, which was developed by Nathaniel Heintz at Rockefeller University (in collaboration with Paul Greengard and Myriam Heiman).

Википедия

Ribosome biogenesis

Ribosome biogenesis is the process of making ribosomes. In prokaryotes, this process takes place in the cytoplasm with the transcription of many ribosome gene operons. In eukaryotes, it takes place both in the cytoplasm and in the nucleolus. It involves the coordinated function of over 200 proteins in the synthesis and processing of the three prokaryotic or four eukaryotic rRNAs, as well as assembly of those rRNAs with the ribosomal proteins. Most of the ribosomal proteins fall into various energy-consuming enzyme families including ATP-dependent RNA helicases, AAA-ATPases, GTPases, and kinases. About 60% of a cell's energy is spent on ribosome production and maintenance.

Ribosome biogenesis is a very tightly regulated process, and it is closely linked to other cellular activities like growth and division.

Some have speculated that in the origin of life, ribosome biogenesis predates cells, and that genes and cells evolved to enhance the reproductive capacity of ribosomes.